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Maleimide functionalized poly(L-lactide-co-glycolide) (PLGA-Maleimide, PLGA-Mal, Mal-PLGA) can be used to prepare nanoparticles, which can be further modified by thiol-reactive entities.
Poly (lactic-co-glycolic acid) (PLGA) is one of the most effective biodegradable polymeric nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems due to controlled and sustained- release properties, low toxicity, and biocompatibility with tissue and cells.
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