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상품명 | PEI-g-PEG-SH |
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판매가 | 견적문의 |
월 렌탈 금액 |
월 원 (개월 기준)
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구매방법 | |
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배송주기 |
정기배송 할인 save
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PEI Molecular Weight | |
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PEG molecular Weight | |
PEG substitution % | |
Package Size | |
옵션선택 |
(최소주문수량 1개 이상 / 최대주문수량 0개 이하)
사이즈 가이드할인가가 적용된 최종 결제예정금액은 주문 시 확인할 수 있습니다.
PEI-g-PEG-SH is a graft copolymer of branched PEI (bPEI), which is modified with multiple SH-PEGs of indicated MW. The PEG to PEI ratio is the average number of PEGs per PEI. Custom service is provided to produce PEG-PEI reagents with any MW of PEI and any MW of PEG at any graft ratio PEG-g(x)-PEI, x is the PEG to PEI ratio.
Copolymers of cationic poly(ethyleneimine) grafted with thiol-polyethylene glycol (PEG) (PEI-g-PEG-SH) are extremely well-studied compounds that markedly improve the in vitro and in vivo delivery of oligonucleotides (AOs) to cells and tissues. By varying the Mw of PEI, as well as the nature of PEG shielding, PEG-PEI-AO nanoparticulates can be prepared with a dynamic range of size, surface charge, and stability. Each of these properties in-turn influences the transfection capacity of the PEG-PEI-AO polyplexes. In addition, PEG-PEI copolymers are readily functionalized for enhanced efficacy and specificity of cellular and tissue targeting.
PEI-g-PEG-SH can be used to prepare cationic nanoparticles for targete gene/AOS delivery. Thiol can y reacts with maleimide and novel metal surface including gold, silver, etc..
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